منابع مشابه
The notochord
the paper, I immediately understood that it was going to be possible to use Agrobacterium to make transgenic plants and that would, in turn, create many new opportunities. I concluded that plant molecular genetics was poised to take off and that insight, plus some nudging from Shauna, tipped me over the edge. What is your greatest frustration? I am frustrated by the influence of political organ...
متن کاملShaping the zebrafish notochord
Cellular reorganization based on active cell motility and adhesion is the major means of morphogenesis in animal embryos, and is particularly elaborated in vertebrates. Nowhere is this fact more clearly shown than in the dorsal mesoderm of gastrulating zebrafish embryos. Here, occurring in the company of both cellular internalization at the blastoderm margin (Carmany-Rampey and Schier, 2001) (R...
متن کاملEph Regulates Dorsoventral Asymmetry of the Notochord Plate and Convergent Extension-Mediated Notochord Formation
BACKGROUND The notochord is a signaling center required for the patterning of the vertebrate embryonic midline, however, the molecular and cellular mechanisms involved in the formation of this essential embryonic tissue remain unclear. The urochordate Ciona intestinalis develops a simple notochord from 40 specific postmitotic mesodermal cells. The precursors intercalate mediolaterally and estab...
متن کاملFine Structure of the Notochord of Amphioxus
The protochordate amphioxus has been a favorite object of study for over a century. Early workers gave particular attention to the notochord of this remarkable animal because of its unique position and structure and its evolutionary significance (1). Modern advances in microscopy have opened the way for new research on the chorda dorsalis. Tenbaum (2) recently examined it under the polarizing m...
متن کاملWnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord
The notochord develops from notochord progenitor cells (NPCs) and functions as a major signaling center to regulate trunk and tail development. NPCs are initially specified in the node by Wnt and Nodal signals at the gastrula stage. However, the underlying mechanism that maintains the NPCs throughout embryogenesis to contribute to the posterior extension of the notochord remains unclear. Here, ...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2004
ISSN: 0960-9822
DOI: 10.1016/j.cub.2004.09.065